Figure 5. Abnormal Functional Connectivity in Essential Tremor.

(A) Functional connectivity between the network hub in the cerebellum and the sensorimotor cortices was significantly different in patients with essential tremor compared with healthy controls. (B) Bar charts (mean ± 95% CI for each group) and individual participant connectivity values show that, on average, these regions were positively connected in healthy controls (left) yet negatively functionally connected in patients with essential tremor (right).