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. 2023 Oct 10;101(15):e1521–e1530. doi: 10.1212/WNL.0000000000207700

Table 2.

Primary and Secondary Analyses of Cortical Atrophy on CT, N = 1,102

graphic file with name WNL-2023-000492t2.jpg

GCA 0 (n = 818) GCA 1 (n = 220) GCA 2/3 (n = 64) GCA 1 vs GCA 0 GCA 2/3 vs GCA 0 GCA ≥ 1 vs GCA0
a/acOR (95% CI) p Value a/acOR (95% CI) p Value a/acOR (95% CI) p Value
90-d mRS, median (IQR) 2 (1–3) 3 (1–5) 3 (2–6) 1.55 (1.15–2.10) 0.005 1.95 (1.18–3.23) 0.009 1.62 (1.22–2.16) 0.001
90-d mRS 0–2, n/N (%) 539/818 (66) 100/220 (46) 26/64 (41) 0.64 (0.43–0.94) 0.023 0.71 (0.37–1.38) 0.311 0.65 (0.45–0.94) 0.02
90-d mRS 6, n/N (%) 80/818 (10) 47/220 (21) 18/64 (28) 2.16 (1.28–3.64) 0.004 1.95 (0.86–4.43) 0.111 2.12 (1.28–3.5) 0.003

Adjustments were made for age, sex, final infarct volume, total WMD-burden, the interaction between alteplase and nerinetide, NIHSS at baseline, stroke laterality, and presence of chronic infarctions.