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. 2023 Oct 18;23:1001. doi: 10.1186/s12885-023-11288-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — Immune cell bubble plots (A). Box plot of the analysis of differences in immune function between high and low risk groups (B). Box plots of high and low risk groups in the analysis of differences in risk groups (C). Stromal score ,The higher the score, the higher the stromal cell content in the tumor microenvironment (D). Immune score, The higher the score, the higher the content of immune cells in the tumor microenvironment (E). Estimate score, The higher the score, the higher the content of stromal cells and immune cells in the tumor microenvironment and the lower the content of tumor cells (F). Differential expression of 41 immune checkpoint expressions in high and low risk groups (G). Violin plot of the analysis of differences in immunotherapy between high and low risk groups (H)