Table 3.
The expression level of SH2D1A was significantly correlated with the expression of immune cell markers in HCC with tumor purity
| Gene | Coefficient | P | Gene | Coefficient | P |
|---|---|---|---|---|---|
| CD8A | 0.85456309 | 1.27E-99 | HLA-DQB1 | 0.583105318 | 8.25E-33 |
| CD8B | 0.743393609 | 7.09E-62 | HLA-DRA | 0.621319185 | 3.20E-38 |
| CD3D | 0.731080308 | 6.62E-59 | HLA-DPA1 | 0.655690032 | 9.07E-44 |
| CD3E | 0.894548317 | 5.35E-122 | CD1C | 0.519231383 | 3.28E-25 |
| CD2 | 0.86471045 | 1.31E-104 | NRP1 | 0.184854906 | 0.000558818 |
| CD19 | 0.547172959 | 2.46E-28 | ITGAX | 0.493683486 | 1.35E-22 |
| CD79A | 0.701937989 | 1.73E-52 | TBX21 | 0.794043823 | 3.79E-76 |
| CD86 | 0.62316122 | 1.68E-38 | STAT4 | 0.558224737 | 1.18E-29 |
| CSF1R | 0.524678418 | 8.50E-26 | STAT1 | 0.543002049 | 7.52E-28 |
| CCL2 | 0.340264645 | 8.47E-11 | IFNG | 0.642013885 | 1.78E-41 |
| CD68 | 0.354422898 | 1.20E-11 | TNF | 0.512228684 | 1.80E-24 |
| IL10 | 0.462535122 | 1.08E-19 | GATA3 | 0.680882767 | 2.55E-48 |
| NOS2 | 0.012074031 | 0.823177975 | STAT6 | 0.152140349 | 0.004623899 |
| IRF5 | 0.197750673 | 0.000218772 | STAT5A | 0.417545542 | 5.48E-16 |
| PTGS2 | 0.286609443 | 6.02E-08 | IL13 | 0.179179251 | 0.00082841 |
| CD163 | 0.498529481 | 4.48E-23 | BCL6 | 0.123503491 | 0.021765188 |
| VSIG4 | 0.374536414 | 6.24E-13 | IL21 | 0.243626764 | 4.70E-06 |
| MS4A4A | 0.509326765 | 3.59E-24 | STAT3 | 0.14196436 | 0.008273776 |
| CEACAM8 | 0.051908934 | 0.336393954 | IL17A | 0.167942121 | 0.001746115 |
| ITGAM | 0.295974154 | 2.10E-08 | FOXP3 | 0.443137012 | 5.01E-18 |
| CCR7 | 0.677354884 | 1.18E-47 | CCR8 | 0.565261309 | 1.61E-30 |
| KIR2DL1 | 0.099904974 | 0.063802467 | STAT5B | 0.224855069 | 2.49E-05 |
| KIR2DL3 | 0.306235488 | 6.34E-09 | TGFB1 | 0.310151688 | 3.96E-09 |
| KIR2DL4 | 0.487657097 | 5.20E-22 | PDCD1 | 0.694787235 | 4.94E-51 |
| KIR3DL1 | 0.269862725 | 3.60E-07 | CTLA4 | 0.690286203 | 3.88E-50 |
| KIR3DL2 | 0.388988451 | 6.57E-14 | LAG3 | 0.60025003 | 3.79E-35 |
| KIR3DL3 | 0.142759694 | 0.007915913 | HAVCR2 | 0.556233637 | 2.06E-29 |
| KIR2DS4 | 0.327847865 | 4.36E-10 | GZMB | 0.570231739 | 3.83E-31 |
| HLA-DPB1 | 0.64683208 | 2.85E-42 |
HCC Hepatocellular carcinoma