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. 2023 Oct 18;21:736. doi: 10.1186/s12967-023-04621-6

Fig. 4.

Fig. 4

RIZ2 overexpression deregulate EGF-R pathway in DLD1 CRC cells. A Bar Chart obtained by IPA (Ingenuity Pathway Analysis) functional annotation analysis showing statistically. Significant pathway enriched following RIZ2 overexpression. B Results of TCGA data analysis. Correlation of RIZ2 (PRDM2-003) and EGFR or EGF mRNA expression in COAD tumor samples obtained by GEPIA2. C Ingenuity Pathway Analysis of the EGF/R (red) pathway highlighting changes in transcripts (blue) induced by RIZ2 overexpression