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. 2023 Oct 18;23:1000. doi: 10.1186/s12885-023-11457-2

Table 2.

Patient and clinical characteristcis of ROS1+ solid tumors

All NSCLC Glioblastoma Breast Other
N (%) 259 204 (79%) 18 (7%) 7 (3%) 30 (11%)
Age median (range) 63 (18–89) 65 (27–89) 63 (41–89) 60 (40–77) 52.5 (18–80)
Male 113 (44%) 86 (42%) 11 (61%) 0 (0%) 16 (53%)
Female 146 (56%) 118 (58%) 7 (39%) 7 (100%) 14 (47%)
Sequencing methods
Targeted RNA Archer (prior to 2019) 55 (21%) 49 (24%) 4 (22%) 1 (14%) 1 (3%)
WTS (post 2019) 204 (79%) 155 (76%) 14 (78%) 6 (86%) 29 (96%)
Mean junction read (SD) 54.7 64 (107.8) 32.2 (55.1) 6.7 (5.2) 25.6 (25.8)
Median TMB 4 4 3 5 4