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. 2023 Oct 19;25:58. doi: 10.1186/s12968-023-00958-5

Table 1.1.

Symptomatic Patients With No Known CCD and No Prior Testing

Clinical Scenario Text ECG Treadmill Stress Nuclear MPI Stress Echo Stress CMR CAC CCTA Cath No Test
1. Less-likely anginal symptoms with a noncardiac explanation R (3) R (2) R (2) R (2) R (3) R (1) R (1) A (8)
2. Less-likely anginal symptoms, age < 50 y and 0 or 1 CV risk factor M (4) R (3) R (3) R (3) M (4) R (3) R (1) A (7)
3. Less-likely anginal symptoms, age 50 y or above and/or ≥ 2 CV risk factors M (6) M (6) M (6) M (5) M (6) M (5) R (2) M (4)
4. Likely anginal symptoms, age < 50 y and 0 or 1 CV risk factor A (7) A (7) A (7) A (7) M (6) A (7) R (3) R (3)
5. Likely anginal symptoms, age 50 y or above and/or ≥ 2 CV risk factors A (7) A (8) A (8) A (7) M (5) A (7) A (7) R (1)

CV risk factors: diabetes mellitus, smoking, family history of premature CAD, hypertension, dyslipidemia

A = Appropriate; CAC = coronary artery calcium; CAD = coronary artery disease; cath = cardiac catheterization; CCD = chronic coronary disease; CCTA = coronary computed tomography angiography; CMR = cardiac magnetic resonance; CV = cardiovascular; ECG = electrocardiogram; echo = echocardiography; M = May Be Appropriate; MPI = myocardial perfusion imaging; R = Rarely Appropriate