Table 5. ADME Analysis of Active Compounds.
| 4h | 4j | 4k | 4l | 4n | |
|---|---|---|---|---|---|
| molecular weight | 473.49 | 487.52 | 471.52 | 502.49 | 526.38 |
| A log P | 4.5 | 4.81 | 5.11 | 4.71 | 6.1 |
| H-bond acceptor | 6 | 6 | 5 | 7 | 5 |
| H-bond donor | 3 | 2 | 2 | 2 | 2 |
| rotatable bonds | 4 | 5 | 4 | 5 | 4 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.