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Cytotoxicity of selected compound in PBL.
| Compounds | PBL restinga GI50 (µM)c |
PBL + PHAb GI50 (µM)c |
|---|---|---|
| 1d | >10 | >10 |
| 1j | >10 | >10 |
| 1m | >10 | >10 |
| 1x | >10 | 6.0 ± 0.8 |
| 1y | >10 | >10 |
| SLC-0111 | >10 | >10 |
PBL not stimulated with PHA.
PBL stimulated with PHA.
Compound concentration required to reduce cell growth by 50%.
