Table 2.

Factors associated with reaching the endpoint in the IgN-NS and IgAN-NR.

Factors	HR	CI	p	HR	CI	p
Age	1.01	0.99–1.02	.4
Serum albumin	0.99	0.96–1.03	.7
Body mass index	1.01	0.98–1.04	.4
C1	1.12	0.69–1.83	.6
E1	0.69	0.37–1.28	.2
Fibrinogen	1.13	0.94–1.37	.2
Hemoglobin	0.77	0.43–1.37	.4
HDL-cholesterol	0.4	0.17–0.95	.04	0.29	0.06–0.84	0.03
LDL-cholesterol	0.93	0.77–1.12	.4
Mean arterial pressure	1.01	1–1.03	.1
M1	2.06	1.02–4.13	.04	1.81	1.22–5.33	.04
Proteinuria	1.07	0.99–1.15	.09	1.07	0.99–1.16	.09
Serum creatinine	0.99	0.91–1.09	.9
Male	1.5	0.92–2.43	.1
S1	2.6	0.92–7.33	.07	2.97	0.90–7.41	.06
Total cholesterol	1.06	0.94–1.2	.3
Triglyceride	0.97	0.86–1.1	.7
T1	1.67	1.15–5.22	.2
T2	0.74	0.39–1.4	.4
Serum IgA	1.12	0.69–1.83	.6
Uric acid	1.17	1.04-1.32	.01	1.14	1.01-1.29	.01
Urine red blood cell count	0.97	0.88–1.06	.5
Renin-angiotensinsystem inhibito	0.99	0.97–1.01	.3
Steroid	0.98	0.9–1.07	.7
Immunosuppressant	0.7	0.37–1.33	.3

The endpoint was defined as a continuous decline in eGFR from baseline of ≥30% or reaching ESRD. Factors that showed statistical significance (p < .1) in univariate-Cox-regression analysis were selected for inclusion in the multivariate-Cox-regression model. The FB stepwise method using AIC was employed to choose the best model with a minimum AIC value.

E1: signifies endocapillary hypercellularity; M1: denotes mesangial hypercellularity; T1-2: refers to the severity of interstitial fibrosis/tubular atrophy; S1: indicates segmental glomerulosclerosis/adhesion; C1: signifies the presence of a crescent; HR: represents the hazard ratio; CI: stands for confidence interval; AIC: represents the Akaike information criterion.