Table 2. The top ten upregulated DEGs and downregulated DEGs of GC-NAG and IM-NAG.
GC-NAG | IM-NAG | Regulation | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Gene | log 2 (FC) | P | P.adjust | Gene | log 2 (FC) | P | P.adjust | |||
Top ten up-regulated DEGs | ||||||||||
SERPINE1 | 6.07 | 3.52E−38 | 7.27E−34 | OTOP3 | 6.95 | 2.37E−32 | 4.48E−28 | Up | ||
ADAMTS4 | 6.63 | 7.12E−36 | 7.35E−32 | HEPH | 4.63 | 6.55E−32 | 6.18E−28 | Up | ||
WNT2 | 14.35 | 4.27E−29 | 2.94E−25 | SLC39A5 | 4.86 | 5.87E−26 | 3.69E−22 | Up | ||
ATP1B3 | 3.1 | 6.44E−28 | 3.32E−24 | HOXA13 | 14.06 | 6.73E−25 | 3.18E−21 | Up | ||
CCN1 | 6.2 | 1.39E−27 | 5.72E−24 | CDH17 | 6.83 | 3.49E−24 | 1.32E−20 | Up | ||
MARCO | 9.28 | 3.50E−27 | 1.13E−23 | TINAG | 14.63 | 8.47E−24 | 2.37E−20 | Up | ||
COL4A1 | 4.31 | 3.82E−27 | 1.13E−23 | ONECUT2 | 5.07 | 8.78E−24 | 2.37E−20 | Up | ||
HEPH | 3.94 | 1.00E−26 | 2.58E−23 | MYO7B | 6.80 | 1.56E−22 | 3.68E−19 | Up | ||
COL6A3 | 4.26 | 4.82E−26 | 1.04E−22 | CPS1 | 7.40 | 2.80E−22 | 5.88E−19 | Up | ||
RGS1 | 5.42 | 5.04E−26 | 1.04E−22 | ADH6 | 5.08 | 3.97E−22 | 7.50E−19 | Up | ||
Top ten down-regulated DEGs | ||||||||||
ABCC5 | −2.09 | 2.65E−24 | 2.28E−21 | AMY2A | −13.77 | 6.75E−07 | 4.04E−05 | Down | ||
RPTN | −9.5 | 6.62E−24 | 5.46E−21 | CTRC | −6.76 | 2.02E−06 | 1.08E−04 | Down | ||
SLC7A8 | −2.78 | 2.07E−23 | 1.58E−20 | SYCP2 | −1.61 | 6.26E−06 | 2.88E−04 | Down | ||
FLG2 | −11.9 | 1.69E−22 | 9.68E−20 | CASR | −1.73 | 6.55E−06 | 2.99E−04 | Down | ||
SYTL2 | −2.64 | 3.97E−22 | 2.15E−19 | CYP2AB1P | −1.52 | 9.28E−06 | 4.09E−04 | Down | ||
CHAD | −3.48 | 2.60E−21 | 1.28E−18 | SUCNR1 | −1.85 | 1.26E−05 | 5.32E−04 | Down | ||
ALDOC | −3.19 | 2.14E−20 | 9.01E−18 | SYCN | −13.53 | 1.36E−05 | 5.68E−04 | Down | ||
SMIM14 | −1.79 | 5.69E−20 | 2.13E−17 | CAMK2B | −1.71 | 1.37E−05 | 5.68E−04 | Down | ||
SGSM3 | −1.89 | 3.11E−19 | 1.05E−16 | PAX6 | −1.67 | 1.87E−05 | 5.68E−04 | Down | ||
RNASE4 | −2.07 | 4.64E−19 | 1.49E−16 | CPLX2 | −2.24 | 1.90E−05 | 7.44E−04 | Down |
Notes.
- DEGs
- differentially expressed genes
- FC
- fold change