Table 2.

TBSS-ROI results: white matter microstructure differences between children with DD and TD controls.

Pathway	Laterality	DTI-measure	Contrast	Voxels	Peak value of p*	Peak MNI Coordinates (mm)			Figures
						X	Y	Z
SLF/AF	L	FA	Controls > Dyscalculia	87	0.023	−38	−23	29	Figure 1
SLF/AF	L	MD	Dyscalculia > Controls	256	0.016	−32	−19	31
SLF/AF	L	RD	Dyscalculia > Controls	72	0.035	−34	−25	35
SLF/AF	L	AD	Dyscalculia > Controls	5	0.046	−37	−14	31	-
ATR	L	AD	Dyscalculia > Controls	195	0.003	−18	8	7	Figure 2
ATR	L	MD	Dyscalculia > Controls	151	0.02	−11	−3	2
CC-Splenium	Bilateral	AD	Dyscalculia > Controls	161	0.008	−1	−36	17	Figure 3
CC-Splenium	Bilateral	MD	Dyscalculia > Controls	121	0.021	−7	−38	20
CC-Body	Bilateral	AD	Dyscalculia > Controls	198	0.025	−1	−12	26
IC	R	AD	Dyscalculia > Controls	352	0.016	15	−7	0	Figure S2
IC	R	MD	Dyscalculia > Controls	294	0.016	22	−7	12
IC	L	AD	Dyscalculia > Controls	197	0.02	−10	−2	1	Figure S3
IC	L	MD	Dyscalculia > Controls	77	0.036	−19	3	12
SCR	R	FA	Controls > Dyscalculia	88	0.024	27	−11	20	Figure S2
SCR	L	RD	Dyscalculia > Controls	14	0.048	−25	−9	33	-
ATR	R	AD	Dyscalculia > Controls	4	0.047	17	7	7	-

^*Corrected for multiple comparisons with FWE correction at p < 0.05 level with TFCE method.

FA, Fractional anisotropy; AD, Axial diffusivity; MD, Mean diffusivity; RD, Radial diffusivity; SLF/AF, Superior longitudinal fasciculus/arcuate fasciculus; ATR, Anterior thalamic radiation; CC, Corpus callosum; IC, Internal capsule; SCR, Superior corona radiata.