Human peripheral blood T-helper-cell responses to recall antigens (PPD, TT) and to superantigen (SEB) in the absence (AY−) or in the presence (AY+) of 3 × 10−6 M AY. −Ag, no antigen. The proliferation was studied with PBMCs from six HIV positive subjects (subjects S1 and S2, [CD4+-cell counts, >500/mm3] and subjects M1 to M4 [CD4+-cell counts, <200/mm3) or from one healthy seronegative donor (HIV−). Results are expressed as counts per minute of [3H]thymidine incorporated in cultures at 6 days after stimulation (the results are means ± SDs of three experimental values).