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. 2023 Oct 2;8(41):38092–38100. doi: 10.1021/acsomega.3c04187

Table 5. Modified Draize’s Grading Scale for Evaluating the Ocular Irritation Potential of Substances.

irritation appearance irritation intensity score
conjunctival discharge normal 0
slight discharge 1
sever discharge covering a small area around the cornea 2
sever discharge covering a large around the cornea 3
conjunctival chemosis normal 0
slight chemosis including the nictitating membrane 1
severe chemosis with the eye partially closed 2
severe chemosis with the eye closed 3
conjunctival redness blood vessel normal 0
some blood vessel definitely hyperemic 1
diffuse color, individual vessel not easily discernible 2
diffuse beefy red 3