TABLE 1.

Correlations Between Behavioral Scores and ¹¹C-CHDI-180R V_T Values in Gray Matter Structures

Gray matter structure	Neurologic rating		Working memory
	Correlation	P	Correlation	P
Dorsolateral prefrontal cortex	0.522	0.056	−0.6120	0.034*
Ventrolateral prefrontal cortex	0.533	0.050*	−0.6220	0.031*
Orbitofrontal cortex	0.406	0.150	−0.5770	0.050*
Ventromedial prefrontal cortex	0.443	0.112	−0.5550	0.0610
Dorsomedial prefrontal cortex	0.672	0.008†	−0.6630	0.019*
Anterior cingulate cortex	0.703	0.005†	−0.6370	0.026*
Dorsal premotor cortex	0.504	0.066	−0.5870	0.045*
Ventral premotor cortex	0.594	0.025*	−0.5980	0.040*
Supplemental motor cortex	0.667	0.009†	−0.6130	0.034*
Primary motor cortex	0.451	0.106	−0.5550	0.061
Superior temporal cortex	0.419	0.136	−0.5450	0.067
Inferior temporal cortex	0.406	0.150	−0.5360	0.072
Rhinal cortex	0.374	0.187	−0.5270	0.078
Insular cortex	0.566	0.035*	−0.5680	0.054
Somatosensory cortex	0.432	0.123	−0.5540	0.062
Parietal cortex	0.388	0.170	−0.5350	0.073
Posterior cingulate cortex	0.46	0.098	−0.5650	0.056
Occipital cortex	0.375	0.187	−0.5160	0.086
Caudate	0.51	0.063	−0.5720	0.052
Putamen	0.589	0.027*	−0.5930	0.042*
Internal globus pallidus	0.458	0.100	−0.5310	0.076
External globus pallidus	0.511	0.062	−0.5570	0.060
Lateral thalamus	0.402	0.155	−0.5210	0.082
Medial thalamus	0.387	0.172	−0.5060	0.093
Hippocampus	0.434	0.121	−0.5390	0.071
Amygdala	0.473	0.088	−0.5520	0.063
Substantia nigra	0.43	0.125	−0.5740	0.051
Cerebellum	0.423	0.132	−0.5370	0.072

^*P < 0.05.

^†P < 0.01.

Higher neurologic rating scores, and lower working memory scores, are associated with greater impairment. Correlations are 2-tailed Pearson. (Buffer, n = 5; 10Q, n = 4; 85Q, n = 5.)