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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Gastroenterology. 2023 Feb 8;164(6):921–936.e1. doi: 10.1053/j.gastro.2023.01.039

Figure 1 -. Tet1 and Tdg inactivation modifies tumor multiplicity or size in the ApcMin background.

Figure 1 -

Box plots representations of number (A) and size distribution (B) of colonic and small intestinal adenomas in Tet1−/−Tdg+/+ApcMin/+ mice; Tet1+/−TdgN151A/+ApcMin/+ mice; Tet1+/+TdgN151A/+ApcMin/+ mice, and control Tet1+/+Tdg+/+ApcMin/+ mice. Small intestinal adenomas were binned in: <2mm, 2–3mm and >3mm. (C) Histopathological analysis of adenomas of different genotypes stained by hematoxylin-eosin and visualized at 10x (top row; scale bar=50 microns) and 20x magnification (bottom row; scale bar=10 microns). (D) Frequency of surface erosion in adenomas of different genotypes. **p-value <0.01, ***p-value <0.001.