Fig 4. Effect of the input number of virions on viral replication dynamics across tissues.

Each line represents a single run of the stochastic model. A: Number of virions in the midgut epithelium (M_v) and B: Number of virions in the hemocoel (H_v). Parameter values for all simulations were: the rate virions infect susceptible cells, β = 10⁻⁷ h⁻¹; virus decay rate, μ_v = 0.1 h⁻¹; virus production rate γ = 10 h⁻¹; rate virions spread between cells, α = 10⁻⁶ h⁻¹; and virus escape through the basal lamina, ρ = 0.005 h⁻¹.