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. 2023 Oct 19;18(10):e0293043. doi: 10.1371/journal.pone.0293043

Fig 4. tRF-003634 alleviates Adr-induced podocyte injury by reducing the stability of TLR4 mRNA through YTHDC1.

Fig 4

(A) The binding of tRF-003634 to YTHDC1. (B) The binding of TLR4 to YTHDC1. (C) The interference efficiency of YTHDC1 was determined using the qRT-PCR. (D) Expression levels of TLR4 mRNA were detected by qRT-PCR after the knockdown of YTHDC1. (E) Expression levels of TLR4 mRNA were evaluated by qRT-PCR after the overexpression of tRF-003634. n = 3, *P<0.05 vs. respective NC. YTHDC1 NC, YTHDC1 siRNA negative control; tRF-003634 NC, tRF-003634 negative control.