Figure 4.
Effect of c.180C>T variant on CTRC mRNA expression. A, Electropherograms showing Sanger sequencing of a cDNA sample from the pancreas of a heterozygous CTRC c.180 C>T carrier. Note the difference in the peak heights at position c.180. B, Relative mRNA expression levels of the c.180T CTRC allele in the pancreas of heterozygous c.180C>T carriers. The gray line and symbols represent the calibration curve; the black triangles denote the pancreatic cDNA samples analyzed (n=10). See Methods for experimental details.
