TABLE 1.
Results of the detection of non-synonymous and indel mutations described for the Omicron variant (on 29 November 2021) using different sequencing techniques: Oxford Nanopore, Illumina, and Sanger
| Gene | SNP/indel | Amino acid substitution | Oxford Nanopore sequencing | Illumina sequencing | Sanger sequencing |
|---|---|---|---|---|---|
| ORF1ab | A2832G | K856R | G | G | NA b |
| ORF1ab | 6513_6515del | del2084/2084 | A-[GTT]A | A-[GTT]A | NA |
| ORF1ab | G8393A | A2710T | A | A | NA |
| ORF1ab | C10029T | T3255I | T | T | NA |
| ORF1ab | C10449A | P3395H | A | A | NA |
| ORF1ab | 11288_11296del | del3674/3676 | A-[GTTTGTCTG]G | A-[GTTTGTCTG]G | NA |
| ORF1ab | G11287T | L3674F | T | T | NA |
| ORF1ab | A11537G | I3758V | G | G | NA |
| ORF1ab | C14408T | P4715L | T | T | NA |
| ORF1ab | A18163G | I5967V | G | G | NA |
| S | C21762T | A67V | T | T | T |
| S | 21765_21770del | del69/70 | A-[TACATG]T | A-[TACATG]T | A-[TACATG]T |
| S | C21846T | T95I | T | T | T |
| S | G21987A | G142D | A | A | A |
| S | 21987_21995 | del143/145 | G-[GTGTTTATT]A | G-[GTGTTTATT]A | G-[GTGTTTATT]A |
| S | 22194_22196del | del212/212 | A-[ATT]T | A-[ATT]T | NR |
| S | 22205GAGCCAGAAins | 215EPEins | GAGCCAGAA | GAGCCAGAA | NR |
| S | G22578A | G339D | A | A | A |
| S | T22673C, C22674T | S371L | CT | CT | CT |
| S | T22679C | S373P | C | C | C |
| S | C22686T | S375F | T | T | T |
| S | G22813T | K417N | NR a | NR | T |
| S | T22882G | N440K | NR | NR | G |
| S | G22898A | G446S | NR | NR | A |
| S | G22992A | S477N | A | A | A |
| S | C22995A | T478K | A | A | A |
| S | A23013C | E484A | C | C | C |
| S | A23040G | Q493R | G | G | G |
| S | G23048A | G496S | A | A | A |
| S | A23055G | Q498R | G | G | G |
| S | A23063T | N501Y | T | T | T |
| S | T23075C | Y505H | C | C | C |
| S | C23202A | T547K | A | A | A |
| S | A23403G | D614G | G | G | G |
| S | C23525T | H655Y | T | T | T |
| S | T23599G | N679K | G | G | G |
| S | C23604A | P681H | A | A | A |
| S | C23854A | N764K | A | A | NR |
| S | G23948T | D796Y | T | T | NR |
| S | C24130A | N856K | A | A | A |
| S | A24424T | Q954H | T | T | T |
| S | T24469A | N969K | A | A | A |
| S | C24503T | L981F | T | T | T |
| E | C26270T | T9I | T | T | NA |
| M | A26530G | D3G | G | G | NA |
| M | C26577G | Q19E | G | G | NA |
| M | G26709A | A63T | A | A | NA |
| N | C28311T | P13L | T | T | NA |
| N | 28362_28370del | del31/33 | G-[GAGAACGCA] | G-[GAGAACGCA] | NA |
| N | G28881A, G28882A, G28883C | RG203KR | AAC | AAC | NA |
a
NR, no result.
b
NA, not available.