TABLE 4.
Gene | Known association | Reference |
---|---|---|
COL11A2, COL6A6, COL9A1 | OPLL susceptibility gene | 30 |
FGF2 | OPLL susceptibility gene | 6 |
TGF β1 | Insulin-dependent chondrogenesis | 28 |
RSPO4 and LEMD3 | DISH protective gene | 7 |
TLR1 | OPLL susceptibility gene | 30 |
FGF, fibroblast growth factor; FGF2, fibroblast growth factor 2 gene; OPLL, ossification of the posterior longitudinal ligament.
PubMed search results for peer-reviewed literature of known genetic associations with DISH and OPLL are summarized.