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. 2023 Oct 12;2023:8022356. doi: 10.1155/2023/8022356

Table 4.

In silico toxicological properties of the Ehretia species phytoconstituents.

ID Ligands hERG blocker Mutagenicity Tumorigenicity Reproductive effect Human hepatotoxicity
Requirements 0 ~ 0.3 0 ~ 0.3
DB01 Buddlenol B 0.15 None None None 0.293
DB05 Ehletianol A 0.101 None None None 0.016
DB06 Ehletianol B 0.062 None None None 0.011
DB07 Ehletianol D 0.104 Low High None 0.318
DB09 Caffeic anhydride 0.007 None None None 0.242
DB10 Icariside E5 0.071 None None None 0.404
DB11 Lithospermic acid B 0.025 None None None 0.381
DB12 Methyl rosmarinate 0.032 None None None 0.227
DB16 Hyperoside 0.017 None None None 0.144
DB19 Quercetin 0.099 High High None 0.1
DB28 Ehretioside B 0.009 None None None 0.082
DB63 Rutin 0.017 None None None 0.092
DB64 Lucenin 2 0.035 High High Low 0.147
DB66 Riboflavin 0.029 None None None 0.118

hERG: human Ether-à-go-go-Related Gene.