Table 2. Different ECLS configuration as a bridge to LTx.

ECLS configuration	Cannulation	Support provided	Patient conditions
VV ECMO	Peripheral (double lumen cannula in the SVC via the jugular or subclavian vein or single lumen cannula in the femoral vein or jugular and femoral vein)	Respiratory	Hypoxemia
VA ECMO	Peripheral (femoral vessels; jugular/subclavian vein and subclavian artery)	Respiratory + circulatory	Hypoxemia with hemodynamic instability
VAV ECMO	Same as VA ECMO + additional cannula in the jugular vein	Respiratory + circulatory	Hypoxemia + severe right heart dysfunction (in case of inadequate oxygenation of the upper body)
VVA ECMO	Same as VV ECMO + additional cannula in the subclavian artery	Respiratory + circulatory	Hypoxemia + severe right heart dysfunction
ECCO2-R	Peripheral (veno-venous or veno-arterial)	Respiratory	Hypercapnia

ECLS, extracorporeal life support; LTx, lung transplantation; VV, veno-venous; VA, veno-arterial; VAV, veno-arteriovenous; VVA, veno-venoarterial; ECMO, extracorporeal membrane oxygenation; ECCO₂-R, extracorporeal carbon dioxide removal; SVC, superior vena cava.