Table 2.
Effect of exercise on incident mild cognitive impairment and dementia
| Certainty assessment | No. of patients | Effect | Certainty | Importance | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Intervention | Controls | Relative (95% CI) | Absolute (95% CI) | ||
| Any dementia | ||||||||||||
| 1 | Randomized controlled trial | Not serious | Not serious | None | Very seriousa | None | 28/818 (3.4%) | 29/817 (3.5%) |
OR 0.96 (0.57–1.63) |
1 fewer per 1.000 (from 15 fewer to 21 more) |
⨁◯◯◯ Very low |
Critical |
| Mild cognitive impairment | ||||||||||||
| 1 | Randomized controlled trial | Not serious | Not serious | None | Very seriousa | None | 70/686 (10.2%) | 62/682 (9.1%) |
OR 1.14 (0.79–1.62) |
11 more per 1.000 (from 18 fewer to 49 more) |
⨁◯◯◯ Very low |
Critical |
CI confidence interval, OR odds ratio
aOnly one study with wide confidence intervals