Table 5.
MRI diagnostic performance on axillary lymph node in current study combined with literature review
| Author | Journal/Year | Patient numbers | Reference standard | Sensitivity (%) | Specificity (%) | NPV (%) | PPV (%) | Accuracy (%) |
|---|---|---|---|---|---|---|---|---|
| Yoshimura et al. [13] | Breast Cancer/1999 | 202 | ALND | 79 | 93 | 87 | 89 | 88 |
| Kvistad et al. [14] | Eur Radiol/2000 | 65 | ALND | 83 | 90 | 90 | 83 | 88 |
| Orguc et al. [15] | Balkan Med J/2012 | 155 | ALND | 89 | 14 | 80* | 21.4* | Not reported |
| He et al. [16] | Eur J Radiol/2012 | 136 | ALND | 33.3–86.5 | 95.2–98.2 | 1.9–16.7 | 66.7–82.6 | 18.5–96.2 |
| Scaranelo et al. [17] | Radiology/2012 | 61 | ALND/SLNB | 88.4 | 82.4 | 94.7 | 69.4 | 85 |
| Hwang et al. [18] | J Breast Cancer/2013 | 349 | ALND/SLNB | 47.8 | 88.7 | 82.6 | 60.2 | 77.9 |
| Hieken et al. [19] | Surgery/2013 | 505 | ALND/SLNB | 54.2 | 78.2 | 75.7 | 57.7 | 69.7 |
| Abe et al. [20] | Acad Radiol/2013 | 50 | ALND/SLNB | 60 | 79 | 81 | 59 | 74 |
| An et al. [21] | Nuklearmedizin/2014 | 132 | ALND | 67.5 | 78 | 79.2 | 65.9 | 74 |
| Arslan et al. [22] | Springerplus/2016 | 35 | SLNB | 73.3 | 95 | 82.6 | 91.7 | 85.7 |
| Hyun et al. [23] | Eur J Radiol/2016 | 425 | ALND/SLNB | 51.3 | 92.2 | 83.3 | 71.4 | 80.9 |
| Barco et al. [24] | Clin Transl Oncol/2016 | 1351 | ALND/SLNB | 29.8 | 96.6 | 68.4 | 84.9 | Not reported |
| Atallah et al. [25] | Breast J/2020 | 169 | ALND/SLNB | 70.3 | 87.5 | 76.2 | 83.3 | Not reported |
| Zhao et al. [26] | Eur J Radiol/2020 | 265 | ALND/SLNB | 72.7 | 87.1 | 71 | 94.3 | Not reported |
| Chen et al. | Current study | 2473# | ALND/SLNB | 63.2 (544/861) | 68.5 (1104/1612) | 77.7 (1104/1421) | 51.7 (544/1052) | 66.6 (1648/2473) |
MRI magnetic resonance imaging, PPV positive predictive value, NPV negative predictive value, ALND axillary lymph node dissection, SLNB sentinel lymph node biopsy
*Calculated parameters
#All these 2473 cases were primary operable invasive breast cancer patients