Table 2.
Histopathologic findings at kidney biopsy
| Diagnosis according to ISN/RPS | n (%) | SLICC criteria: proteinuria ≥ 0.5 g/24 h or u-ACR ≥ 30 mg/mmol and/or red blood cell casts in sediment; n (%)* | EULAR/ACR criteria: proteinuria ≥ 0.5 g/24 h or u-ACR ≥ 30 mg/mmol; n (%)* |
|---|---|---|---|
| LN | 123 (88.5) | 107/113 (94.7) | 83/111 (74.8) |
| Classes I and II | 25 (20.3) | 19/20 (95.0) | 9/17 (52.9) |
| Classes III and IV | 72 (58.5) | 65/68 (95.6) | 56/70 (80.0) |
| Class V | 26 (21.1) | 23/25 (92.0) | 18/24 (75.0) |
| Non-LN | 16 (11.5) | 12/14 (85.7) | 8/12 (66.7) |
| Vasculitis | 7 | 6/6 | 5/6 |
| Hypertensive nephrosclerosis | 3 | 2/3 | 1/2 |
| aPLN | 2 | 1/2 | 1/2 |
| IgAn | 1 | 1/1 | 1/1 |
| TIN | 1 | – | – |
| tGBM | 1 | 1/1 | 0/1 |
| No overt findings | 1 | 1/1 | - |
ISN/RPS, International Society of Nephrology/Renal Pathology Society; u-ACR: urine albumin-to-creatinine ratio; aPLN, anti-phospholipid assiociated nephropathy; IgAn, IgA nephropathy; TIN, tubulointerstitial nephropathy; tGBM, thin glomerular basement membranes; n, number
*Data missing in a subset of patients