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. 2023 Jul 24;182(10):4407–4420. doi: 10.1007/s00431-023-05091-0

Table 1.

Characteristics & laboratory data of 24 patients (baseline & after treatment values)

Patient’s no. Indication Duration of
treatment
(days)
Sex Age
(years,
months)
Weight
(kg)
Height
(cm)
Bilirubin
(mg/dl)
[T > up to 1.0]
Albumin
(g/l)
[3.5–5.5]
Serum creatinine
( mg/dl)
[0.6–1.4]
ALT
(GPT)
(IU/L)
[Up to 40]
AST
(GOT)
(IU/L)
[Up to 40]
eGFR**
(Schwartz Formula)
(ml/min/1.73 m2)
B* A# B A B A B A B A B A
1 Pneumonia 14 F

0 Y

9 M

9.5 70 0.2 0.28 3.7 3.9 1.1 0.5 10 20 27 35 26.3 57.8
2 Meningitis 10 F

0 Y

2.5 M

1.7 40 0.2 0.25 3.3 3.5 0.3 0.4 30 35 55 68 55.1 41.3
3 Urinary Tract Infection 5 F

3 Y

0 M

17.5 94 0.1 0.3 0.87 0.87 0.3 0.1 8.4 15 31.8 40 129.4 388.2
4 Peritonitis 14 M

9 Y

0 M

24 133.5 0.08 0.2 1.87 1.4 0.23 0.1 18.8 29 25.6 29 239.7 551.4
5 Infective Endocarditis 21 M

4 Y

0 M

14 103 0.3 0.4 4.35 3.74 1.96 1.06 4.1 13.8 9.4 37 21.7 40.1
6 Meningitis 10 M

12 Y

0 M

35 150 0.1 0.2 4.2 4.2 0.63 0.5 15 17 24 28 98.3 123.9
7 Pneumonia 14 F

1 Y

10 M

11 76 0.2 0.27 4.5 4.5 0.38 0.36 14 16 20 22 82.6 87.2
8 Meningitis 10 M

0 Y

8 M

9 70 0.1 0.2 4.1 4.1 0.5 0.42 15 20 50 60 57.8 68.8
9 Meningitis 14 M

0 Y

5 M

7.5 66 0.1 0.23 4 4 0.53 0.5 19 23 40 49 51.4 54.5
10 Pneumonia 7 F

2 Y

2 M

10.3 77 0.2 0.25 4.5 4.5 0.64 0.55 12 17 23 61 49.7 57.8
11 Meningitis 10 F

11 Y

0 M

34 145 0.2 0.29 4.4 4.4 1 0.9 16 18 25 29 59.9 66.5
12 Meningitis 10 F

1 Y

4 M

11.5 76 0.1 0.22 4.3 4.3 0.6 0.4 18 20 20 21 52.3 78.5
13 Gastroenteritis 7 M

1 Y

7 M

11 75 0.4 0.9 4.32 4.26 0.21 0.21 48.8 55 59.9 65 147.5 147.5
14 Meningitis, Gastroenteritis 10 M

0 Y

5 M

6.8 66 0.1 0.2 4 4.2 0.46 0.32 18 25 38 40 59.3 85.2
15 Gastroenteritis 7 F

0 Y

3 M

6.6 60 0.2 0.25 4.5 4.4 0.36 0.3 45.1 50 74 77 68.8 82.6
16 Meningitis 10 F

11 Y

0 M

15 154 0.2 0.27 4.35 4.3 0.64 0.5 51 54 75 79 99.4 127.2
17 Meningitis 7 M

0 Y

4 M

5.5 65 0.1 0.19 4.55 4.5 0.4 0.30 25 30 36 40 67.1 89.5
18 Urinary Tract Infection 5 F

5 Y

0 M

19 108 0.1 0.15 1.84 2 1.6 1.2 25 35 39 45 27.9 37.2
19 Pneumonia 14 F

0 Y

11 M

12 73 0.2 0.27 3.7 3.9 0.6 0.5 15 20 29 35 50.2 60.3
20 Meningitis 10 F

1 Y

0 M

13 78 0.28 0.35 3.2 3.3 0.5 0.4 39 45 49 69 64.4 80.5
21 Pneumonia 14 F

4 Y

0 M

16 107 0.2 0.4 4 4.2 1.85 1.4 25 29 45 50 23.9 31.6
22 Cystitis 7 M

10 Y

0 M

37 158 0.29 0.5 3 3.2 0.72 0.65 27 30 39 45 90.6 100.4
23 Gastroenteritis 7 M

0 Y

6 M

8 66 0.2 0.4 3.8 3.7 0.35 0.3 42 46 53 69 77.9 90.9
24 Pneumonia 14 M

6 Y

5 M

22 116 0.2 0.27 3.78 3.9 0.8 0.7 19 25 38 45 59.9 68.4
Median 10 1.705 11.75 76.5 0.2 0.27 4 4.05 0.565 0.46 18.9 25 38 45 59.9 79.5
Minimum 5 0.21 1.7 40 0.08 0.15 0.87 0.87 0.21 0.1 4.1 13.8 9.4 21 21.7 31.6
Maximum 21 12 37 158 0.4 0.9 4.55 4.5 1.96 1.4 51 55 75 79 239.7 551.4

*B baseline value; #A is the value after treatment with ceftriaxone

** According to National Kidney Foundation (NKF), eGFR of 90 or higher is in the normal range, 60–89 may mean early kidney disease, 15–59 may indicate kidney disease and below 15 may mean kidney failure

ALT alanine aminotransferase, AST aspartate aminotransferase, eGFR estimated glomerular filtration rate. year, M month