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. 2023 Sep 20;42(11):1285–1296. doi: 10.1007/s10096-023-04648-z

Table 4.

Available antimicrobial drugs with activity against Stenotrophomonas maltophilia

Antibiotic Dosage
Trimethoprim-sulfamethoxazole 8-12 mg/kg/die IV* divided every 8 hours or every 12 hours
Levofloxacin 750 mg IV*/po** every 24 hours
Minocycline 200 mg IV*/po** every 12 hours
Tigecycline 200 mg IV* (first dose) then 100 mg IV* every 12 hours
Cefiderocol 2 g IV* every 8 hours infused over 3 hours
Ceftazidime-avibactam 2.5 g IV* over 3 hours every 8 hours
Aztreonam 2 g IV* over 2 hours every 8 hours

*Intravenous dosing

**Oral dosing