Table 1.
Patient preferences regarding outcome measures (PFS and QoL)
| Preference | All patients | |||
|---|---|---|---|---|
| Long PFS | High QoL | None | ||
| Number of patients | 92 | 81 | 21 | 194 |
| Advanced treatment line | ||||
| Yes | 21 (11%) | 32 (16%) | 11 (6%) | 64 (33%) |
| No | 71 (37%) | 49 (25%) | 10 (5%) | 130 (67%) |
| Fisher exact test statistic value < 0.021 | The result is significant at p < 0.05 | |||
| Number of patients | 90 | 79 | 21 | 190 |
| Tendency to hand over responsibility to physicians | ||||
| Yes | 31 (16%) | 14 (7%) | 7 (4%) | 52 (27%) |
| No | 59 (31%) | 65 (34%) | 15 (8%) | 138 (73%) |
| Fisher exact test statistic value < 0.0153 | The result is significant at p < 0.05 | |||
| Number of patients | 92 | 76 | 18 | 186 |
| Diarrhoea | ||||
| Mild or none | 79 (42%) | 65 (35%) | 16 (9%) | 160 (86%) |
| Severe or very severe | 13 (7%) | 11 (6%) | 2 (1%) | 26 (14%) |
| Fisher exact test statistic value = 1 | The result is not significant at p < 0.05 | |||
| Number of patients | 90 | 75 | 19 | 184 |
| Nausea | ||||
| Mild or none | 87 (47%) | 72 (39%) | 19 (10%) | 178 (97%) |
| Severe or very severe | 3 (1.5%) | 3 (1.5%) | 0 | 6 (3%) |
| Fisher exact test statistic value = 1 | The result is not significant at p < 0.05 | |||
| Number of patients | 90 | 75 | 18 | 183 |
| Constipation | ||||
| Mild or none | 84 (46%) | 69 (38%) | 18 (9%) | 171 (93%) |
| Severe or very severe | 6 (3%) | 6 (3%) | 0 | 12 (6%) |
| Fisher exact test statistic value = 0.77 | The result is not significant at p < 0.05 | |||
| Number of patients | 90 | 76 | 19 | 185 |
| Fatigue | ||||
| Mild or none | 70 (38%) | 60 (32%) | 15 (8%) | 145 (78%) |
| Severe or very severe | 20 (11%) | 16 (9%) | 4 (2%) | 40 (22%) |
| Fisher exact test statistic value = 1 | The result is not significant at p < 0.05 | |||
| Number of patients | 92 | 76 | 19 | 187 |
| Fever | ||||
| Yes | 2 (1%) | 4 (2%) | 0 | 6 (3%) |
| No | 90 (48%) | 72 (39%) | 19 (10%) | 181 (97%) |
| Fisher exact test statistic value = 0.41 | The result is not significant at p < 0.05 | |||
| Number of patients | 90 | 73 | 19 | 182 |
| Upper airway infection | ||||
| Mild or none | 90 (49%) | 70 (38%) | 19 (10%) | 179 (96%) |
| Severe or very severe | 0 | 3 (2%) | 0 | 3 (2%) |
| Fisher exact test statistic value = 0.09 | The result is not significant at p < 0.05 | |||
| Number of patients | 90 | 76 | 19 | 185 |
| Pulmonary infection | ||||
| Mild or none | 85 (46%) | 74 (40%) | 19 (10%) | 178 (96%) |
| Severe or very severe | 5 (3%) | 2 (1%) | 0 | 7 (4%) |
| Fisher exact test statistic value = 0.46 | The result is not significant at p < 0.05 | |||
| Number of patients | 90 | 75 | 19 | 184 |
| Dyspnea | ||||
| Mild or none | 81 (44%) | 69 (38%) | 18 (9%) | 168 (91%) |
| Severe or very severe | 9 (5%) | 6 (3%) | 1 (1%) | 16 (9%) |
| Fisher exact test statistic value = 0.79 | The result is not significant at p < 0.05 | |||
| Number of patients | 91 | 76 | 19 | 186 |
| Vertigo | ||||
| Mild or none | 85 (46%) | 72 (39%) | 19 (10%) | 176 (95%) |
| Severe or very severe | 6 (3%) | 4 (2%) | 0 | 10 (5%) |
| Fisher exact test statistic value = 0.76 | The result is not significant at p < 0.05 | |||
| Number of patients | 91 | 75 | 19 | 185 |
| Sensory peripheral neuropathy | ||||
| Mild or none | 83 (45%) | 66 (36%) | 18 (9%) | 167 (90%) |
| Severe or very severe | 8 (4%) | 9 (5%) | 1 (1%) | 18 (10%) |
| Fisher exact test statistic value = 0.61 | The result is not significant at p < 0.05 | |||
| Number of patients | 89 | 75 | 19 | 183 |
| Secondary malignancy | ||||
| Yes | 6 (3%) | 3 (2%) | 1 (1%) | 10 (6%) |
| No | 83 (45%) | 72 (39%) | 18 (10%) | 173 (94%) |
| Fisher exact test statistic value = 0.51 | The result is not significant at p < 0.05 | |||
| Number of patients | 92 | 74 | 18 | 184 |
| General muscular weakness | ||||
| Yes | 35 (19%) | 32 (17%) | 9 (5%) | 76 (41%) |
| No | 57 (31%) | 42 (23%) | 9 (5%) | 108 (59%) |
| Fisher exact test statistic value = 0.53 | The result is not significant at p < 0.05 | |||
| Number of patients | 89 | 76 | 19 | 184 |
| Muscle cramps | ||||
| Mild or none | 74 (40%) | 62 (34%) | 17 (9%) | 153 (83%) |
| Severe or very severe | 15 (8%) | 14 (8%) | 2 (1%) | 31 (17%) |
| Number of patients | 91 | 76 | 19 | 186 |
| Thrombosis/thromboembolism | ||||
| Yes | 14 (8%) | 11 (6%) | 4 (2%) | 29 (16%) |
| No | 77 (41%) | 65 (35%) | 15 (8%) | 157 (84%) |
| Fisher exact test statistic value = 1 | The result is not significant at p < 0.05 | |||
| Number of patients | 88 | 78 | 21 | 187 |
| Back pain | ||||
| Yes | 10 (5%) | 4 (2%) | 3 (1%) | 17 (9%) |
| No | 78 (42%) | 74 (40%) | 18 (9%) | 170 (91%) |
| Fisher exact test statistic value = 0.17 | The result is not significant at p < 0.05 | |||
| Number of patients | 88 | 79 | 21 | 188 |
| Hip pain | ||||
| Yes | 87 (46%) | 78 (41%) | 21 (11%) | 186 (99%) |
| No | 1 (1%) | 1 (1%) | 0 | 2 (1%) |
| Fisher exact test statistic value = 1 | The result is not significant at p < 0.05 | |||
| Number of patients | 91 | 80 | 20 | 191 |
| Arm or shoulder pain | ||||
| Yes | 46 (24%) | 51 (27%) | 8 (4%) | 105 (55%) |
| No | 45 (24%) | 29 (15%) | 12 (63%) | 86 (45%) |
| Fisher exact test statistic value = 0.09 | The result is not significant at p < 0.05 | |||
| Number of patients | 89 | 78 | 21 | 188 |
| Chest pain | ||||
| Yes | 24 (13%) | 27 (14%) | 9 (5%) | 60 (32%) |
| No | 65 (35%) | 51 (27%) | 12 (6%) | 128 (68%) |
| Fisher exact test statistic value = 0.32 | The result is not significant at p < 0.05 | |||
| Number of patients | 91 | 81 | 21 | 193 |
| Dry mouth | ||||
| Yes | 50 (26%) | 45 (23%) | 12 (6%) | 107 (55%) |
| No | 41 (21%) | 36 (19%) | 9 (5%) | 86 (45%) |
| Fisher exact test statistic value = 1 | The result is not significant at p < 0.05 | |||
| Number of patients | 90 | 78 | 21 | 189 |
| Hair loss | ||||
| Yes | 20 (11%) | 20 (11%) | 6 (3%) | 46 (24%) |
| No | 70 (37%) | 58 (31%) | 15 (8%) | 143 (76%) |
| Fisher exact test statistic value = 0.72 | The result is not significant at p < 0.05 | |||
| Number of patients | 91 | 81 | 21 | 193 |
| Heartburn | ||||
| Yes | 41 (21%) | 32 (17%) | 12 (6%) | 85 (44%) |
| No | 50 (26%) | 49 (25%) | 9 (5%) | 108 (56%) |
| Fisher exact test statistic value = 0.54 | The result is not significant at p < 0.05 | |||
| Number of patients | 86 | 78 | 21 | 185 |
| Lenalidomide maintenance therapy | ||||
| At the time of the survey | 68 (36%) | 48 (26%) | 18 (10%) | 134 (72%) |
| Before the time of the survey | 18 (10%) | 30 (16%) | 3 (2%) | 51 (28%) |
| Fisher exact test statistic value = 0.0164 | The result is significant at p < 0.05 | |||