TABLE 2.
Estimation of the kill-rate parameter derived from the Emax model which fitted the data from the in vitro static time–kill curve at an interval of 0–9 h.
| Group | Emax (log10 CFU/mL/h) | EC50 (μg/mL) | Hill coefficient | R2 |
|---|---|---|---|---|
| A | 0.57 | 0.18 | 1.64 | 0.990 |
| B | 0.48 | 0.05 | 1.71 | 0.996 |
| C | 1.25 | 0.90 | 0.18 | 0.986 |
| D | 0.52 | 0.04 | 1.78 | 1.000 |
Emax, maximum value of the kill rate at an interval of 0–9 h; EC50, concentration at which 50% of the maximum kill rate was reached; R 2, correlation coefficient of the relationship between the experimental value and predicted value (A) Enrofloxacin used alone with strain ZJ42 (B) Cefquinome used alone with strain ZJ42. Cefquinome in combination with enrofloxacin for the strains (C) ZJ42-1.5 s and (D) CLS2.