TABLE 3.

MIC values of drug-resistant bacteria, the types of drug resistance and the relative fitness value (W).

Drug	Bacterial numbering	MIC (mg/L)					Resistant type	W
		Enrofloxacin	Enrofloxacin + CCCP	The multiplier of enrofloxacin MIC	Cefquinome	The multiplier of cefquinome MIC
enrofloxacin alone	ZJ42-0.75 mg/kg (Total)	0.50	0.25	4	0.13	—	aac (6′)-lb-cr mutant	24 h: 0.40
								48 h: 0.8
	ZJ42-1.25 mg/kg (Total)	0.50	0.50	4	0.13	—	aac (6′)-lb-cr mutant	24 h: 1.38
								48 h: 1.35
	ZJ42-1.5 mg/kg (Split-12 h)	1	1	8	0.13	—	aac (6′)-lb-cr mutant	24 h: 1.61
								48 h: 1.77
cefquinome alone	ZJ42-4 mg/kg (Split-8 h)	0.13	0.13	—	0.5	4	—	—
cefquinome combine	CLS2-1 mg/kg (Split-12 h)	8	8	4	1	8	—	—