Table 1.
Baseline characteristics of patients in LoDoCo2 stratified by DM status.
| Type 2 diabetes (n = 1,007) | No diabetes (n = 4,515) | p-valuea | |
|---|---|---|---|
| Demographics | |||
| Age, mean (SD), years | 66.7 (8.0) | 65.6 (8.7) | <0.001 |
| Female, No. (%) | 144 (14.3) | 702 (15.5) | 0.32 |
| Clinical characteristics | |||
| Hypertension, No. (%) | 628 (62.4) | 2,180 (48.3) | <0.001 |
| Current smoker, No. (%) | 127 (12.7) | 521 (11.6) | 0.34 |
| Insulin-dependent DM, No. (%) | 287 (28.5) | ||
| Creatinine clearance <60 ml/min/1.73 m2, No. (%) | 76 (7.5) | 230 (5.1) | <0.01 |
| Prior acute coronary syndrome, No. (%) | 843 (83.7) | 3,815 (84.5) | 0.54 |
| Prior coronary revascularization, No. (%) | 856 (85.0) | 3,765 (83.4) | 0.21 |
| Coronary artery bypass grafting, No. (%) | 189 (18.8) | 521 (11.5) | <0.001 |
| Percutaneous coronary intervention, No. (%) | 743 (73.8) | 3,434 (76.1) | 0.13 |
| History of atrial fibrillation, No. (%) | 138 (13.7) | 511 (11.3) | 0.03 |
| Medication at enrollment | |||
| Single antiplatelet therapy, No. (%) | 654 (64.9) | 3,047 (67.5) | 0.12 |
| Dual antiplatelet therapy, No. (%) | 234 (23.2) | 1,046 (23.2) | 0.96 |
| Anticoagulant, No. (%) | 144 (14.3) | 528 (11.7) | 0.02 |
| No antiplatelet agent or anticoagulant, No. (%) | 3 (0.3) | 12 (0.3) | 0.86 |
| Statin, No. (%) | 938 (93.1) | 4,250 (94.1) | 0.24 |
| Renin angiotensin inhibitor, No. (%) | 815 (80.9) | 3,145 (69.7) | <0.001 |
| Beta-blocker, No. (%) | 695 (69.0) | 2,732 (60.5) | <0.001 |
a
p-values for comparison between groups were calculated using the chi-square test for proportions and independent sample t-test for means.