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. 2023 Oct 10;9(10):e20850. doi: 10.1016/j.heliyon.2023.e20850

Supplementary Table 1High-risk factors for the survival of HBV-related HCC on entire enrolled patients


Univariable
Multivariable
HR (95%CI) P HR (95%CI) P
Age ≥60 years 1.292 (1.100–1.518) 0.002 1.209 (1.027–1.424) 0.023
Male 1.470 (1.171–1.845) 0.001 1.293 (1.025–1.631) 0.030
ALB <35 g/L 2.826 (2.424–3.295) <0.001 1.491 (1.248–1.780) <0.001
AST ≥80 U/L 3.863 (3.292–4.532) <0.001 1.818 (1.517–2.177) <0.001
TBIL ≥34 μmol/L 2.975 (2.514–3.521) <0.001 1.174 (0.964–1.430) 0.111
PLT <100 × 109/L 1.669 (1.434–1.942) <0.001 1.114 (0.946–1.313) 0.196
AFP (take <20 ng/mL as a reference)
20–400 ng/mL 3.505 (2.825–4.349) <0.001 2.284 (1.830–2.852) <0.001
≥400 ng/mL 5.724 (4.583–7.149) <0.001 2.746 (2.168–3.479) <0.001
LSM (take <9 kPa as a reference)
9–22 kPa 2.846 (2.120–3.822) <0.001 2.266 (1.684–3.049) <0.001
≥22 kPa 8.333 (6.213–11.176) <0.001 4.326 (3.201–5.847) <0.001
BCLC (take 0/A as a reference)
B/C 6.386 (5.292–7.706) <0.001 4.079 (3.348–4.971) <0.001
D 27.574 (20.173–37.690) <0.001 16.830 (12.048–23.509) <0.001

Note: ALB albumin; AST, aspartate aminotransferase; TBIL, total bilirubin; PLT, platelet; AFP, alpha-fetoprotein; LSM, liver stiffness measurement; BCLC, Barcelona Clinic Liver Cancer; HR, hazard ratio; CI, confidence interval.