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. 2023 Oct 6;11:1266940. doi: 10.3389/fbioe.2023.1266940

TABLE 3.

Interocular consistency test of corneal biomechanical parameters in the control and keratoconus groups.

Control (n = 331) Keratoconus (n = 207)
Biomechanical parameters OD OS ICC a p for ICC Better eye Worse eye ICC a p for ICC
Pachy [μm] 556.91 ± 30.98 557.7 ± 31.75 0.956 <0.001 506.47 ± 42.85 475.24 ± 38.46 0.588 <0.001
A1T [ms] 7.38 ± 0.29 7.40 ± 0.28 0.857 <0.001 7.29 ± 0.26 7.16 ± 0.26 0.720 <0.001
A1V [m/s] 0.15 ± 0.02 0.15 ± 0.02 0.725 <0.001 0.16 ± 0.02 0.17 ± 0.02 0.421 <0.001
A2T [ms] 21.51 ± 0.46 21.52 ± 0.46 0.844 <0.001 22.20 ± 0.55 22.33 ± 0.56 0.846 <0.001
A2V [m/s] −0.28 ± 0.03 −0.28 ± 0.03 0.621 <0.001 −0.29 ± 0.04 −0.31 ± 0.05 0.388 <0.001
HCT [ms] 16.84 ± 0.57 16.91 ± 0.51 0.365 <0.001 17.17 ± 0.54 17.16 ± 0.52 0.260 <0.001
PD [mm] 5.33 ± 0.27 5.31 ± 0.26 0.770 <0.001 5.37 ± 0.26 5.39 ± 0.25 0.727 <0.001
A1DeflAmp [mm] 0.09 ± 0.01 0.09 ± 0.01 0.258 <0.001 0.09 ± 0.01 0.10 ± 0.01 0.295 <0.001
HCDeflAmp [mm] 0.95 ± 0.10 0.94 ± 0.10 0.810 <0.001 1.02 ± 0.11 1.10 ± 0.13 0.579 <0.001
A2DeflAmp [mm] 0.10 ± 0.01 0.10 ± 0.01 0.369 <0.001 0.10 ± 0.01 0.11 ± 0.02 0.211 0.001
A1DeflArea [mm2] 0.17 ± 0.03 0.19 ± 0.04 0.164 0.001 0.17 ± 0.03 0.19 ± 0.03 0.122 0.039
HCDeflArea [mm2] 3.61 ± 0.52 3.57 ± 0.51 0.779 <0.001 3.81 ± 0.56 4.04 ± 0.60 0.671 <0.001
A2DeflArea [mm2] 0.22 ± 0.04 0.22 ± 0.04 0.256 <0.001 0.22 ± 0.05 0.24 ± 0.06 0.233 <0.001
A1ΔArcL [mm] −0.02 ± 0.00 −0.02 ± 0.00 0.433 <0.001 −0.02 ± 0.00 −0.02 ± 0.01 0.319 <0.001
HCΔArcL [mm] −0.12 ± 0.02 −0.12 ± 0.02 0.647 <0.001 −0.11 ± 0.03 −0.11 ± 0.03 0.499 <0.001
A2ΔArcL [mm] −0.02 ± 0.00 −0.02 ± 0.00 0.498 <0.001 −0.02 ± 0.01 −0.02 ± 0.01 0.323 <0.001
MaxIR [mm-1] 0.17 ± 0.01 0.17 ± 0.01 0.583 <0.001 0.19 ± 0.02 0.22 ± 0.03 0.293 <0.001
DAR2 3.95 ± 0.35 3.94 ± 0.34 0.873 <0.001 4.62 ± 0.60 5.37 ± 0.90 0.294 <0.001
DAR1 1.51 ± 0.04 1.50 ± 0.04 0.749 <0.001 1.57 ± 0.06 1.63 ± 0.07 0.394 <0.001
ARTh 608.71 ± 118.78 675.69 ± 140.06 0.781 <0.001 420.04 ± 150.92 244.59 ± 100.13 0.278 <0.001
bIOP [mmHg] 15.62 ± 2.16 15.74 ± 2.16 0.799 <0.001 14.63 ± 2.05 14.03 ± 2.19 0.655 <0.001
IR [mm-1] 7.98 ± 0.83 7.91 ± 0.89 0.798 <0.001 9.74 ± 1.53 11.64 ± 1.88 0.345 <0.001
SP-A1 117.61 ± 15.38 115.02 ± 16.35 0.782 <0.001 88.52 ± 20.72 67.22 ± 20.45 0.509 <0.001
SSI 0.85 ± 0.12 0.86 ± 0.13 0.770 <0.001 0.79 ± 0.14 0.70 ± 0.13 0.475 <0.001

Data are presented as mean ± SD.

OD, right eye; OS, left eye; better eye, eye with a lower KSS, grade; worse eye, eye with a greater KSS, grade; ICC, intraclass correlation coefficient.

a

ICC, was calculated using Two-way random model and Consistency type.