. 2023 Oct 6;11:1266940. doi: 10.3389/fbioe.2023.1266940

TABLE 4.

Interocular asymmetry values in the control and keratoconus of different severities.

Biomechanical parameters	Control (n = 331)	Keratoconus (n = 207)	p ^a	KSS of the worse eye in the keratoconus group					p ^b
Biomechanical parameters	Control (n = 331)	Keratoconus (n = 207)	p ^a	KSS 1 (n = 21)	KSS 2 (n = 73)	KSS 3 (n = 64)	KSS 4 (n = 31)	KSS 5 (n = 18)	p ^b
Pachy [μm]	7.13 ± 6.06	37.42 ± 31	<0.001	26.1 ± 43.71	28.12 ± 25.4	31.69 ± 17.62	53.26 ± 26.19	81.44 ± 33.76	<0.001
A1T [ms]	0.11 ± 0.1	0.19 ± 0.15	<0.001	0.14 ± 0.1	0.16 ± 0.14	0.18 ± 0.15	0.27 ± 0.17	0.25 ± 0.13	<0.001
A1V [m/s]	0.01 ± 0.01	0.02 ± 0.02	<0.001	0.01 ± 0.01	0.01 ± 0.01	0.02 ± 0.01	0.03 ± 0.02	0.02 ± 0.02	<0.001
A2T [ms]	0.19 ± 0.17	0.27 ± 0.2	<0.001	0.23 ± 0.17	0.25 ± 0.18	0.26 ± 0.2	0.36 ± 0.24	0.27 ± 0.22	<0.001
A2V [m/s]	0.02 ± 0.02	0.04 ± 0.03	<0.001	0.03 ± 0.03	0.03 ± 0.02	0.04 ± 0.03	0.05 ± 0.04	0.06 ± 0.04	<0.001
HCT [ms]	0.48 ± 0.39	0.5 ± 0.41	0.604	0.63 ± 0.43	0.49 ± 0.43	0.38 ± 0.29	0.61 ± 0.45	0.59 ± 0.51	0.128
PD [mm]	0.13 ± 0.12	0.15 ± 0.11	0.021	0.15 ± 0.14	0.16 ± 0.13	0.14 ± 0.1	0.16 ± 0.12	0.15 ± 0.09	0.293
A1DeflAmp [mm]	0.01 ± 0.01	0.01 ± 0.01	<0.001	0.01 ± 0	0.01 ± 0.01	0.01 ± 0.01	0.02 ± 0.01	0.03 ± 0.02	<0.001
HCDeflAmp [mm]	0.05 ± 0.04	0.11 ± 0.09	<0.001	0.06 ± 0.05	0.08 ± 0.07	0.12 ± 0.08	0.16 ± 0.11	0.16 ± 0.09	<0.001
A2DeflAmp [mm]	0.01 ± 0.01	0.02 ± 0.02	<0.001	0.01 ± 0.02	0.01 ± 0.01	0.02 ± 0.01	0.03 ± 0.02	0.04 ± 0.02	<0.001
A1DeflArea [mm²]	0.03 ± 0.04	0.03 ± 0.03	0.001	0.02 ± 0.02	0.03 ± 0.02	0.03 ± 0.02	0.05 ± 0.03	0.06 ± 0.05	<0.001
HCDeflArea [mm²]	0.26 ± 0.23	0.41 ± 0.33	<0.001	0.3 ± 0.3	0.37 ± 0.3	0.4 ± 0.32	0.55 ± 0.42	0.42 ± 0.27	<0.001
A2DeflArea [mm²]	0.04 ± 0.03	0.05 ± 0.05	0.001	0.05 ± 0.07	0.04 ± 0.04	0.05 ± 0.04	0.07 ± 0.06	0.11 ± 0.09	<0.001
A1ΔArcL [mm]	0 ± 0	0 ± 0	<0.001	0 ± 0	0 ± 0	0 ± 0	0.01 ± 0	0.01 ± 0.01	<0.001
HCΔArcL [mm]	0.01 ± 0.01	0.02 ± 0.02	<0.001	0.02 ± 0.03	0.02 ± 0.02	0.02 ± 0.02	0.03 ± 0.03	0.04 ± 0.03	<0.001
A2ΔArcL [mm]	0 ± 0	0.01 ± 0.01	<0.001	0 ± 0	0.01 ± 0	0.01 ± 0	0.01 ± 0.01	0.02 ± 0.01	<0.001
MaxIR [mm^-1]	0.01 ± 0.01	0.04 ± 0.03	<0.001	0.02 ± 0.02	0.03 ± 0.02	0.04 ± 0.02	0.05 ± 0.03	0.05 ± 0.03	<0.001
DAR2	0.13 ± 0.11	0.92 ± 0.74	<0.001	0.49 ± 0.49	0.61 ± 0.48	0.94 ± 0.52	1.54 ± 1	1.59 ± 0.84	<0.001
DAR1	0.02 ± 0.02	0.07 ± 0.06	<0.001	0.05 ± 0.03	0.05 ± 0.04	0.07 ± 0.05	0.12 ± 0.07	0.11 ± 0.06	<0.001
ARTh	82.57 ± 71.51	192.14 ± 131.32	<0.001	125.74 ± 90.59	182.06 ± 120.45	192.18 ± 114.31	230.17 ± 156.36	244.8 ± 186.62	<0.001
bIOP [mmHg]	1.04 ± 0.91	1.39 ± 1.25	0.009	1.17 ± 0.92	1.3 ± 1.15	1.31 ± 1.2	1.91 ± 1.69	1.39 ± 1.13	0.076
IR [mm⁻¹]	0.41 ± 0.37	2.21 ± 1.62	<0.001	1.15 ± 0.9	1.57 ± 1	2.28 ± 1.32	3.57 ± 2.03	3.44 ± 2.18	<0.001
SP-A1	8.03 ± 7.19	23.9 ± 17.49	<0.001	12.87 ± 8.11	16.65 ± 13.45	25.01 ± 14.44	35.74 ± 19.43	41.78 ± 21.2	<0.001
SSI	0.07 ± 0.06	0.13 ± 0.11	<0.001	0.09 ± 0.07	0.11 ± 0.09	0.14 ± 0.1	0.2 ± 0.14	0.14 ± 0.12	<0.001

Data are presented as mean ± SD.

KSS, keratoconus severity score.

The interocular asymmetry value, the absolute value of the right eye minus that of the left eye.

^{^a}

p for Mann‒Whitney U test between the control and keratoconus groups.

^{^b}

p for Kruskal‒Wallis test among the keratoconus patients with different severities.