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. 2023 Oct 6;14:1269451. doi: 10.3389/fimmu.2023.1269451

Figure 1.

Figure 1

Schematic diagram of the metabolic pathway of iron in the human body and regulatory targets of genes that modulate iron metabolism. DcytB, duodenal cytochrome b; DMT1, divalent metal transporter 1; FPN, ferroportin; HP, hephaestin; TF, transferrin; TFR1, transferrin receptor 1; TFR2, transferrin receptor 2; STEAP3, six-transmembrane epithelial antigen of prostate 3; ROS, reactive oxygen species; ATG, autophagy associated gene; NCOA4, nuclear receptor coactivator 4; IRPs, iron response element binding proteins; PCBP, poly(rC)-binding proteins; HSP, heat shock protein; NRF2, nuclear factor erythroid 2-related factor 2.