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. 2023 Oct 6;14:1269451. doi: 10.3389/fimmu.2023.1269451

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Copyright © 2023 Zhang, Liu, Wang, Guo, Wang, Luo, Huang and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The synthesis process of GSH, and the conversion between oxidized and reduced GPX4. SLC7A11, solute carrier family 7 member 11; SLC3A2, solute carrier family 3 member 2; GCL, glutamate cysteine ligase; GS, glutathione synthase; L–OOH, lipid peroxides; L-OH, alcohol; SeOH, selenenic acid; Se–H, selenol; Se-SG, selenium- glutathione adduct; GR, glutathione reductase.