Table 4.

Parametric comparisons of hyperreflective foci of different diameters.

Variable, in WR	Morphology-related parameters		Variable, in WR	Distribution-related parameters
	Pre-IVI, n = 11	P		Pre-IVI, n = 11	P
$Q_{NS}$ $Q_{HD}$	60 (26–101) 239 (76–411)	0.003	$D_{NS,\mathit{\text{fovea}}}$ $D_{HD,\mathit{\text{fovea}}}$	991.35 (959.52–1072.49) 982.67 (921.75–1028.42)	0.062
$Q_{HD}$ $Q_{HC}$	239 (76–411) 20 (8–37)	0.003	$D_{HD,\mathit{\text{fovea}}}$ $D_{HC,\mathit{\text{fovea}}}$	982.67 (921.75–1028.42) 985.87 (909.17–1093.25)	1.0
$Q_{NS}$ $Q_{HC}$	60 (26–101) 20 (8–37)	0.003	$D_{NS,\mathit{\text{fovea}}}$ $D_{HC,\mathit{\text{fovea}}}$	991.35 (959.52–1072.49) 985.87 (909.17–1093.25)	0.286
$V_{NS}$ $V_{HD}$	2.88 × 105 (1.14 × 105–3.68 × 105) 9.22 × 106 (2.56 × 106–1.30 × 107)	0.003	$D_{NS,RPE}$ $D_{HD,RPE}$	216.45 (204.38–239.87) 213.52 (188.28–230.87)	0.424
$V_{HD}$ $V_{HC}$	9.22 × 106 (2.56 × 106–1.30 × 107) 1.18 × 107 (1.53 × 106–2.86 × 107)	0.131	$D_{HD,RPE}$ $D_{HC,RPE}$	213.52 (188.28–230.87) 213.86 (202.93–273.82)	0.110
$V_{NS}$ $V_{HC}$	2.88 × 105 (1.14 × 105–3.68 × 105) 1.18107 (1.53 × 106–2.86 × 107)	0.003	$D_{NS,RPE}$ $D_{HC,RPE}$	216.45 (204.38–239.87) 213.86 (202.93–273.82)	0.062

¹The variable was expressed as the median (IQR); the p value was obtained by Wilcoxon Signed Rank Test. ² WR, the whole retinal layer; IVI, intravitreal injection; $Q_{NS}$, noise signal quantity; $Q_{HD}$, hyperreflective dots quantity; $Q_{HC}$, hyperreflective clump quantity; $V_{NS}$ noise signal volume; e; $V_{HD}$, hyperreflective dots volume; $V_{HC}$, hyperreflective clump volume; $D_{NS,\mathit{\text{fovea}}}$, distance between noise signal and fovea; $D_{HD,\mathit{\text{fovea}}}$, distance between hyperreflective dots and fovea; $D_{HC,\mathit{\text{fovea}}}$, distance between hyperreflective clumps and fovea; $D_{NS,RPE}$, distance between noise signal and RPE; $D_{HD,RPE}$, distance between hyperreflective dots and RPE; $D_{HC,RPE}$, distance between hyperreflective clumps and RPE.