Table 5.

Comparison of parameters between pre-IVI and post-IVI.

	WR			IR			OR
	Pre-IVI, n = 11	Post-IVI, n = 11	P	Pre-IVI, n = 11	Post-IVI, n = 11	P	Pre-IVI, n = 11	Post-IVI, n = 11	P
$Q_{NS}$	60 (26–101)	64 (24–84)	0.247	14 (9–36)	15 (9–20)	0.241	43 (21–94)	48 (15–63)	0.533
$Q_{HD}$	239 (76–411)	210 (71–232)	0.003	33 (20–75)	23 (12–49)	0.173	216 (59–318)	168 (55–209)	0.006
$Q_{HC}$	20 (8–37)	27 (13–40)	0.213	0 (0–1)	0 (0–1)	0.317	19 (8–37)	27 (12–38)	0.213
$V_{NS}$	2.88 × 105 (1.14 × 105–3.68 × 105)	2.47 × 105 (1.05 × 105–3.54 × 105)	0.033	5.32 × 104 (3.40 × 104–1.35 × 105)	5.27 × 104 (3.85 × 104–9.58 × 104)	0.374	2.16 × 105 (9.22 × 104–3.45 × 105)	1.94 × 105 (6.43 × 104–2.57 × 105)	0.047
$V_{HD}$	9.22 × 106 (2.56 × 106–1.30 × 107)	5.66 × 106 (2.55 × 106–8.45 × 106)	0.003	9.71 × 105 (5.74 × 105–2.04 × 106)	7.61 × 105 (2.86 × 105–1.32 × 106)	0.155	7.67 × 106 (1.84 × 106–1.05 × 107)	4.52 × 106 (2.10 × 106–7.69 × 106)	0.006
$V_{HC}$	1.18 × 107 (1.53 × 106–2.85 × 107)	9.97 × 106 (4.65 × 106–2.66 × 107)	0.929	0 (0–1.53 × 105)	0 (0–2.11 × 105)	0.345	1.18 × 107 (1.53 × 106–2.84 × 107)	9.97 × 106 (4.65 × 106–2.66 × 107)	0.929
$D_{NS,\mathit{\text{fovea}}}$	991.35 (959.52–1072.49)	1042.95 (1014.85–1064.91)	0.534	1103.94 (1057.83–1212.58)	1086.73 (1030.12–1237.50)	0.534	954.27 (906.40–1023.99)	1011.02 (960.74–1060.23)	0.594
$D_{HD,\mathit{\text{fovea}}}$	980.67 (921.75–1028.42)	1005.93 (973.22–1066.87)	0.131	1035.34 (919.43–1184.14)	1014.14 (956.53–1106.73)	0.79	1000.76 (888.70–1024.25)	1011.21 (948.34–1083.34)	0.131
$D_{HC,\mathit{\text{fovea}}}$	985.87 (909.17–1093.25)	970.50 (833.29–1020.72)	0.79	0 (0–909.00)	0 (0–664.33)	0.893	9983.01 (909.17–1093.25)	970.50 (833.29–1022.10)	0.79
$D_{NS,RPE}$	216.45 (204.38–239.87)	190.71 (160.61–202.84)	0.026	293.66 (260.66–322.31)	234.73 (197.79–246.13)	0.013	191.16 (179.96–214.40)	174.93 (147.46–185.65)	0.075
$D_{HD,RPE}$	213.52 (188.28–230.87)	177.60 (162.27–200.99)	0.008	278.50 (270.14–336.15)	242.80 (210.56–249.98)	0.016	196.62 (181.72–211.72)	172.52 (149.30–192.06)	0.004
$D_{HC,RPE}$	213.86 (202.93–273.82)	177.44 (167.83–204.70)	0.004	0 (0–274.30)	0 (0–242.46)	0.686	213.28 (202.93–273.82)	177.44 (167.83–204.70)	0.004
CMT	401 (383–490)	315 (253–367)	0.003

¹the variable was expressed as the median (IQR); the P value was obtained by Wilcoxon Signed Rank Test. ²WR, the whole retinal layer; IR, the inner retinal layer; OR, the outer retinal layer; IVI, intravitreal injection; $Q_{NS}$, noise signal quantity; $Q_{HD}$, hyperreflective dots quantity; $Q_{HC}$, hyperreflective clump quantity; $V_{NS}$, noise signal volume; $V_{HD}$, hyperreflective dots volume; $V_{HC}$, hyperreflective clump volume; $D_{NS,\mathit{\text{fovea}}}$, distance between noise signal and fovea; $D_{HD,\mathit{\text{fovea}}}$, distance between hyperreflective dots and fovea; $D_{HC,\mathit{\text{fovea}}}$, distance between hyperreflective clumps and fovea; $D_{NS,RPE}$, distance between noise signal and RPE; $D_{HD,RPE}$, distance between hyperreflective dots and RPE; $D_{HC,RPE}$, distance between hyperreflective clumps and RPE; CMT, central macular thickness.