Table 4.
List of the Top SNPs Found to Be Associated With Neuropathic Ocular Pain Symptoms via Genome Wide Association Study
| Chr | Position (GRCH38) | rsid | Cohort MAF | P Value | Functional Consequence | Genes |
|---|---|---|---|---|---|---|
| 11 | 134968716 | rs140293404 | 0.03 | 1.23E-08 | intronic | Lnc-B3GAT1-2 (ENSG00000287251) |
| 12 | 115412447 | rs61931467 | 0.03 | 8.41E-08 | intergenic | TBX3, MED13L |
| 18 | 26229978 | rs74942254 | 0.17 | 1.36E-07 | intronic | TAF4B |
| 2 | 41795441 | rs78163327 | 0.045 | 2.30E-07 | intergenic | SLC8A1, LOC388942 |
| 7 | 106585971 | rs60979431 | 0.02 | 2.85E-07 | intergenic | NAMPT, CCDC71L |
| 1 | 208763936 | rs6701123 | 0.16 | 4.00E-07 | intergenic | PLXNA2, MIR205HG |
| 19 | 1720333 | rs4807953 | 0.33 | 4.10E-07 | intergenic | TCF3, ONECUT3 |
| 1 | 109855735 | rs144685507 | 0.02 | 4.60E-07 | intergenic | EPS8L3, CSF1 |
| 6 | 147726229 | rs113491581 | 0.02 | 4.73E-07 | intergenic | SAMD5, SASH1 |
| 1 | 208764239 | rs11585407 | 0.004 | 4.98E-07 | intergenic | PLXNA2, MIR205HG |
Chr = chromosome; MAF = minor allele frequency; rsid = reference SNP cluster ID; SNP = single nucleotide polymorphism.