The incidence of angioid streaks (AS) and pseudoxanthoma elasticum (PXE). The age-stratified incidence rate of AS (A) and the age- and sex-stratified incidence rate of AS (B) are presented. Overall, a bimodal peak was observed in the 60 to 64 and 70 to 74 age groups. By sex, bimodal peaks were observed in males aged 60 to 64 and 85 to 89 years, and in females aged 60 to 64 and 70 to 74 years. The second peak occurred later in males than in females. These bimodalities may reflect the phenotypic variation of AS. Similarly, the age-stratified incidence rate of PXE (C) and the age- and sex-stratified incidence rate of PXE (D) are presented. Overall, a peak was observed in the 70 to 74 age group without any bimodal peaks as seen in AS. By sex, a bimodal peak was observed in males aged 60 to 64 and 80 to 84 years, while in females, a peak was observed in the 70 to 74 age group.