Table 2.
Lesion characteristics by analysis population.
| FA (N) | ITT (N) | PP (N) | ||
|---|---|---|---|---|
| Total | 611 | 587 | 585 | |
| No. of Lesions assessed (count = number of participants) | 1 | 532 | 505 | 504 |
| 2 | 38 | 38 | 38 | |
| 3 | 2 | 2 | 2 | |
| Lesion size (mm) | Mean | 9 | 8.6 | 8.6 |
| SD | 4.9 | 3.5 | 3.5 | |
| Median | 8 | 8 | 8 | |
| Minimum | 0.8 | 0.8 | 0.8 | |
| Maximum | 64 | 20 | 20 | |
| Lesion location | Face and scalp | 281 | 271 | 271 |
| Neck | 21 | 21 | 21 | |
| Anterior chest and abdomen | 56 | 55 | 54 | |
| Posterior chest and back | 90 | 85 | 85 | |
| Arms, excluding palms | 80 | 79 | 79 | |
| Palms | 1 | 1 | 1 | |
| Legs, excluding soles | 80 | 73 | 72 | |
| Soles | 2 | 2 | 2 | |
| Patient level of concern | Not concerned | 144 | 138 | 138 |
| A little concerned | 307 | 299 | 299 | |
| Very concerned | 135 | 126 | 124 | |
| Unknown | 25 | 24 | 24 | |
| Experience of reviewing clinician | Foundation doctor | 55 | 54 | 54 |
| Specialty registrar | 20 | 19 | 18 | |
| Consultant | 455 | 440 | 439 | |
| Other/GPwSI | 81 | 74 | 74 | |
| Missing | 0 | 0 | 0 | |
| Lesion change | None | 110 | 104 | 104 |
| Changed color | 20 | 20 | 20 | |
| Symptomatic | 179 | 172 | 172 | |
| Grown a bit | 112 | 109 | 108 | |
| New lesion | 160 | 154 | 154 | |
| Grown a lot | 30 | 28 | 27 | |
| Clinician assessment of likelihood of skin cancer | Unlikely | 224 | 216 | 215 |
| Equivocal | 61 | 59 | 59 | |
| Likely | 211 | 203 | 202 | |
| Highly likely | 115 | 109 | 109 | |
| Biopsy taken | Lesion not referred for biopsy | 167 | 163 | 162 |
| Further clinical review determined no biopsy needed | 7 | 7 | 7 | |
| Biopsy taken | 418 | 398 | 397 | |
| Patient refused biopsy | 5 | 5 | 5 | |
| Other | 14 | 14 | 14 |
FA, Full Analysis; ITT, Intention-to-Treat; PP, Per Protocol; SD, Standard Deviation; GPwSI, General Practitioner with Special Interest. Number of lesions equates to number of lesion records created in the study database, the lesion count is based on clinician provided information on the number of lesions they assessed for each patient.