Table 4.

Clinico-pathological factors associated with distant-metastasis-free survival.

Factors	Univariate			Multivariate
	HR	95% CI	P value	HR	95% CI	P value
Histology, PTC	1.13	0.64 – 1.56	0.1133
Male	0.74	0.21 – 2.09	0.5987
Age ≤ 15 years	3.04	1.16 – 9.43	0.0230	11.00	2.13 – 202.05	0.0018
Bilateral tumors	1.82	0.72 – 4.52	0.1984
Multifocal tumors	1.65	0.65 – 4.73	0.2971
Extrathyroidal extension	2.77	1.05 – 8.61	0.0386	0.63	0.21 – 2.15	0.4449
Tumor size > 4cm	1.83	0.62 – 4.92	0.2587
pN1	5.84	1.20 – 105.40	0.0252	3.02	0.58 – 55.64	0.2209
Post-operative Tg	8.29	1.67 – 150.07	0.0055	7.92	1.57 – 144.23	0.0079
Total thyroidectomy	5.62	0.55 – 17.90	0.4528
Lymph node dissection	2.89	0.59 – 52.05	0.2253

PTC, Papillary thyroid cancer; pN1, pathologic lymph node metastasis.