The binding energy score of the target compounds during EGFR Tk docking study.

Compound	EGFR TK (PDB: 1XKK)
	Binding affinity (kcal mol−1)	Distance from main residue (in Å)		Interaction type
6d	−9.2503	2.54	Met793	Halogen bond
		3.89	Leu718	Hydrophobic
		4.12	Leu844	Hydrophobic
		3.43	Lys745	Hydrophobic
		2.39	Asn842	Hydrophobic
6m	−11.2312	3.34	Met793	H-acceptor
		4.39	Leu718	Hydrophobic
		4.11	Leu844	Hydrophobic
		3.90	Lys745	H-acceptor
		4.42	Cys797	Hydrophobic
6o	−12.6356	2.61	Met793	Halogen bond
		2.72	Leu718	Hydrophobic
		4.09	Leu844	Hydrophobic
		2.90	Lys745	H-acceptor
		4.15	Cys797	Hydrophobic
		3.51	Arg841	Hydrophobic
Lapatinib	−14.0626	2.96	Met793	H-acceptor
		4.55	Leu718	Hydrophobic
		3.30	Leu844	Hydrophobic
		4.66	Lys745	Hydrophobic
		3.49	Cys775	Halogen bond
		3.10	Leu788	Halogen bond
		3.13	Thr790	Halogen bond
		3.12	Arg776	Halogen bond