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. 2023 Oct 5;6:e45226. doi: 10.2196/45226

Table 1.

Demographics and symptoms of respondents with atopic dermatitis (AD), stratified by disease severity.


Mild (n=37) Moderate (n=48) Severe (n=55) All (N=140) P value (between AD severity group comparison)a
Age (years; N=140), n (%)b

18-29 5 (14) 21 (44) 18 (33) 44 (32) .01

30-39 9 (24) 8 (17) 17 (32) 34 (24) .24

40-49 12 (32) 10 (21) 11 (20) 33 (24) .33

≥50 11 (30) 9 (19) 9 (16) 29 (21) .28
Female (n=138), n (%)b 30 (83) 44 (92) 51 (94) 125 (91) .20
Educational level (n=139), n (%)b .17

Basic compulsory educationc 0 (0) 1 (2) 7 (13) 8 (6)

Youth educationd 13 (35) 20 (42) 24 (44) 57 (41)

Higher educatione,f 23 (60) 25 (52) 22 (40) 69 (50)

Education not completed 1 (3) 0 (0) 0 (0) 1 (1)

Other 1 (3) 2 (4) 1 (2) 4 (3)
Age at diagnosis (years; n=139), n (%)

0-2 14 (38) 19 (40) 31 (56) 64 (46) .11

3-12 14 (38) 10 (21) 8 (15) 32 (23) .04

Older than 12 yearsg .33


13-19 3 (8) 4 (9) 6 (11) 13 (9)


20-40 4 (11) 9 (19) 7 (13) 20 (14)


>40 2 (5) 5 (11) 2 (4) 9 (7)

Do not know 0 (0) 0 (0) 1 (2) 1 (1) N/Ah
Comorbidities (N=140), n (%)

Asthma 18 (49) 16 (33) 24 (44) 58 (41) .33

Allergic rhinitis 24 (65) 27 (56) 34 (62) 85 (61) .71

Food allergies 12 (32) 15 (31) 24 (44) 51 (36) .36

No asthma nor allergy 15 (41) 21 (44) 24 (44) 60 (43) .67

Other types of allergies 5 (14) 9 (19) 7 (13) 21 (15) .95
Bothersome symptoms (N=140), n (%)

Itch 29 (78) 47 (98) 55 (100) 131 (94) <.001

Dry skin 32 (87) 45 (94) 54 (98) 131 (94) .08

Red rash 27 (73) 36 (75) 52 (95) 115 (82) .008

Exudation 7 (19) 15 (31) 28 (51) 50 (36) .005

Swelling 9 (24) 15 (31) 26 (47) 50 (36) .06

Poor night’s sleep 6 (16) 15 (31) 39 (71) 60 (43) <.001

Skin pain 16 (43) 22 (46) 41 (75) 79 (56) .002

Other 0 (0) 6 (13) 5 (9) 11 (8) .10

No symptoms 2 (5) 0 (0) 0 (0) 2 (1) .06

aPearson chi-square test for AD severity group comparison. Significance level 5%.

bChi-square goodness-of-fit test for responders’ representativeness with the Danish general population—age: χ2 goodness of fit=47.8, df=3, P<.001; gender: goodness of fit χ21=87.9, P<.001; education: goodness of fit χ21=13.8, P<.001).

cBasic compulsory education includes 9th and 10th grade.

dYouth education includes high school and vocational school.

eHigher education includes bachelor’s, master’s, or PhD programs.

fPearson chi-square test for AD severity group comparison split between higher education or not.

gPearson chi-square test performed for the AD severity group whose age at diagnosis was older than 12 years.

hN/A: not applicable.