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. 2023 Oct 5;9:e45134. doi: 10.2196/45134

Table 3.

Linear regression models demonstrating the moderating effect of current PrEP use on the association between standardized PRHS and HIRI-MSM scores (n=4092).a

Variable Model 1 Model 2 Model 3 Full model
β (95% CI) P value β (95% CI) P value β (95% CI) P value β (95% CI) P value
Intercept 0 (–0.03 to 0.03) 0.99 .05 (0.02 to 0.08) .001 .06 (0.02 to 0.09) <.001 –.11 (–0.21 to –0.01) .04
HIRI-MSMb score, standardized .19 (0.16 to 0.22) <.001 .23 (0.20 to 0.26) <.001 .27 (0.24 to 0.30) <.001 .26 (0.22 to 0.29) <.001
Current PrEPc use N/Ad N/A –.52 (–0.62 to –0.41) <.001 –.31 (–0.43 to –0.19) <.001 –.36 (–0.48 to –0.23) <.001
HIRI:PrEP interaction N/A N/A N/A N/A –.30 (–0.39 to –0.21) <.001 –.30 (–0.39 to –0.21) <.001
Race

Blacke N/A N/A N/A N/A N/A N/A .04 (–0.07 to 0.14) .49

Pardoe N/A N/A N/A N/A N/A N/A .02 (–0.05 to 0.09) .61
Education

University or highere N/A N/A N/A N/A N/A N/A .12 (0.06 to 0.19) <.001
State

Rio de Janeiroe N/A N/A N/A N/A N/A N/A .03 (–0.05 to 0.10) .48

Othere N/A N/A N/A N/A N/A N/A –.01 (–0.08 to 0.06) .73
Sexual orientation

Gaye N/A N/A N/A N/A N/A N/A .11 (0.03 to 0.19) .007
HIV-KAf score, standardized N/A N/A N/A N/A N/A N/A .12 (0.09 to 0.15) <.001
Steady partner

HIV-negativee N/A N/A N/A N/A N/A N/A –.24 (–0.31 to –0.18) <.001

Living with HIV or HIV-unknowne N/A N/A N/A N/A N/A N/A .16 (0.05 to 0.28) .004
Transactional sexe N/A N/A N/A N/A N/A N/A .11 (–0.01 to 0.23) .073
Last HIV test

6 or more months agoe N/A N/A N/A N/A N/A N/A .08 (0.01 to 0.15) .016

Nevere N/A N/A N/A N/A N/A N/A –.06 (–0.17 to 0.04) .24
Adjusted R2 0.034 N/A 0.057 N/A 0.066 N/A 0.103 N/A

aGiven small sample sizes, Asian (n=70), Indigenous (n=30), and respondents with missing data (n=152) were excluded.

bHIRI-MSM: HIV Incidence Risk Index-men who have sex with men.

cPrEP: pre-exposure prophylaxis.

dN/A: not applicable.

eReference categories are as follows: race: White; education: secondary or lower; Brazilian state: São Paulo; sexual orientation: other; steady partner: no steady partner; transactional sex: no; last HIV test: 6 months or less.

fHIV-KA: HIV/AIDS Knowledge Assessment.