Figure 3. Example Predictions From a Deep-Learning Algorithm.

A and C, True positive prediction of progression to geographic atrophy (GA). The attention map shows clustering around the pigment epithelial defect with overlying hyperreflective foci that collapses into a GA lesion (arrowhead) less than 1 year later. B and D, True negative prediction of nonprogression to GA shows model attention directed to several pigment epithelial defects as well as diffusely distributed along the outer retina. At 26 months after prediction, the eye remained without GA.