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. 2023 Sep 28;26(5):534. doi: 10.3892/etm.2023.12233

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Copyright: © Hu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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PPI network construction and identification of the hub genes. (A) PPI network of all the DEFRGs; genes with no connected dots are hidden. (B) Crosstalk between the top 10 hub genes ranked using the MCC algorithm; the deeper the color of the dot, the more advanced the rank order of the hub gene was. (C) Differential expression of hub genes in the IRI samples from GSE58486 and GSE160516; (D) Crosstalk between top 10 hub genes ranked by MCC algorithm and other DEFRGs. DEFRG, differentially expressed ferroptosis related gene; PPI, protein-protein interaction; IRI, ischemia-reperfusion injury.