Table 1.
Description of the antibiotic screened in this study using S. aureus (CD-35) and E. coli (CD-2). The antibiotics marked with an asterisk were used in the training set and their mechanism of action was known.
| # | Antibiotics Name | Mode of Action | Antibiotic Class | Test Strain |
|---|---|---|---|---|
|
| ||||
| 1) | Ciprofloxacin | Interfere with bacterial DNA replication and transcription.40 | Quinolones | S. aureus (CD-35) |
| 2) | Levofloxacin* | |||
| 3) | Moxifloxacin* | |||
|
| ||||
| 4) | Ceftazidime* | Inhibit bacterial cell wall biosynthesis by binding with penicillin-binding proteins.41 | Cephalosporins | |
| 5) | Cefotaxime | |||
|
| ||||
| 6) | Chloramphenicol* | Inhibits synthesis of proteins preventing growth.42 | Chloramphenicol | |
|
| ||||
| 7) | Vancomycin | Disrupt cross-linking of bacterial peptidoglycan cell wall biosynthesis.43 | Glycopeptides | |
|
| ||||
| 1) | Ciprofloxacin | Interfere with bacteria DNA replication and transcription. | Quinolones | E.coli (CD-2) |
| 2) | Levofloxacin | |||
| 3) | Moxifloxacin | |||
|
| ||||
| 4) | Ceftazidime | Inhibit bacterial cell wall biosynthesis by binding with penicillin-binding proteins. | Cephalosporins | |
| 5) | Cefotaxime | |||
|
| ||||
| 6) | Oxacillin | Inhibit bacterial cell wall biosynthesis.44 | β-lactams | |
| 7) | Amoxicillin | |||