Table 4:
Inhibition of cccDNA by selected compounds
| Compound | HepBHAe82_ AlphaLISA_eAg | HepBHAe82_ Cytotoxicity |
|---|---|---|
| EC50 (μM) | CC50 (μM) | |
| HID | ||
| A19 | 1.3 ± 0.39 | >25 |
| HPD | ||
| A13 | 1.5 ± 0.94 | >25 |
| A15 | 0.76 ± 0.71 | >25 |
| A22 | 0.56 ± 0.34 | >25 |
| A23 | 0.56 ± 0.2 | >25 |
| A24 | 0.43 ± 0.11 | >25 |
| A25 | 0.65 ± 0.51 | >25 |